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Hangzhou Yihe Biomedical Technology Co., Ltd.

  • Nonivamide CAS 2444-46-4
  • video

Nonivamide CAS 2444-46-4

Application: food additives, medicine and health care, marine antifouling coatings, wire and cable anti-termite and anti-rodent contraindicators
  • Yihe Biomedical
  • China


Product Introduction


CAS‍‌‍‍‌ Number: 2444-46-4


Key features

The Yihe Biomedical Nonivamide has a CAS of 2444-46-4. There are 95% and 98% purity versions available. It's also referred to in the catalog as synthetic capsaicin. If a buyer wants a spicy active ingredient, a very pure one, that can be more tightly controlled in terms of specification than what's possible with broad chili extract materials, this chemical would be the perfect match.

As per Yihe Biomedical product details, in addition to above, Nonivamide is mostly known for its pain relief, digestion-enhancing, and blood lipid-lowering effects. What elevates it beyond being just a capsaicin-like substance is its very clearly, very concisely and very precisely defined product specification that is coupled with excellent functionality. Nonivamide can be undoubtedly a good option for a capsaicin-like substance while both researchers and product developers who opt for including it in their product are doing so because it is available with a standardized CAS number, different assay levels, and batch documentation.

Generally, the 95% grade is for normal research and development work or if you are aiming at a cost point but balanced; otherwise, the 98% grade is the main choice of those who want very strictly controlled content and who also want to do quality comparison very strictly within the same group. Actually, since Nonivamide exhibits very powerful sensory and functional characteristics, it is strongly suggested that one carry out sample testing at the small scale level first before going for the full scale production.


Usage sectors

As it is commonly known, plant extract-based ingredients are mainly used in food additives, pharmaceuticals, and health products. Nonivamide has been promoted on top of these (other than the antifouling marine paint and wire and cable anti-termite and anti-rodent sectors).

Food additives and health products related to Nonivamide can be developed in various ways, for example, by using a particular formula, dosage, sensory tolerance levels, and target market requirements. On the other hand, technical formulations, which require a highly pungent component to be recognized as an active ingredient, nonivamide may be used as one of the components in marine antifouling coatings, wire or cable protection systems, etc.

Besides a large order, customers need to examine the dispersion, compatibility, odor impact, safety in handling, stability during processing, and final product suitability with their own application ‍‌‍‍‌system.


Company‍‌‍‍‌ Strengths

Due to a strong integration of customer liaison, quality checking, production planning, and export support, Yihe Biomedical is capable of offering Nonivamide to their clients.

They have a commercial office and a point of logistics follow-up in Hangzhou, but the Nanning factory, which is close to the raw material source of the factory, serves as the place of production.

The production at the Nanning factory was formally started in 2019, the factory covers an area of 3300㎡. There are seven 6-ton extraction tanks, and the annual capacity of the plant to handle raw materials is over 2000 tons.

The quality management system consists of raw material traceability, incoming inspection, process control, finished product testing, retained samples, and batch tracking. From one batch to another, raw materials, production records, testing reports, and logistics information are linked. Besides that, Yihe Biomedical has its ISO 9001:2015, HALAL, Kosher certificates and also hold several certificates related to the organic field. ‍‌‍‍‌‍‌‍‍‌‍‌‍‍‌


Why Choose Us


Premarketing‍‌‍‍‌ Sales and Aftermarket Support

Premarketing Sales Support

1. Immediate Response to Questions

If you have any questions, we will get back to you in 2 hours. Besides, you will get the first batch of the pricing & product information from us in 24 hours.

2. Allowance for Sample Taking

Usually, we provide free samples together with the Certificate of Analysis (COA) and user manuals.

3. Expert Advice

 We can provide you with the help you want especially if you are not clear about your market regulations e.g. US Dietary Supplement cGMP, EFSA standards.

4. Tailored Sample Making

After a customer shares the recipe, based on it, a very small quantity of the product is produced in the lab for delivery time 3-5 working days.


Aftermarket Support

1. Instruction for Use

 Technical data sheets (TDS) are available from us, and they include information on a product's solubility, compatibility & contraindications, recommended dosage, storage conditions, and more.

2. Handling of Customer Complaints

For quality-related issues, within 48 hours there will be a workgroup set up to offer a free replacement/refund, plus the Quality Director will make a corrective action report.

3. Constant Concern for Customer Satisfaction

In addition to sending updated CoAs, literature, and other application research materials related to products from the same batch, we also contact customers every 3 months instead of waiting for them to get in touch with us.

4. Long-Term Stock Planning

We have a safety stock of our best-selling items (≥3 months’ typical usage) kept on hand to assist with avoiding production stoppages and are very committed to this policy.


FAQ

Q1: What product is named by CAS 2444-46-4?

A: This CAS number is assigned to the product Nonivamide, which is the synthetic capsaicin.

Q2: How many different grades/types are available?

A: Yihe Biomedical can produce Nonivamide of 95% and 98% purity levels.

Q3: What are the functions officially claimed?

A: Pain relief, digestive tract stimulation, and lowering blood lipids are the functions officially claimed.

Q4: Which major industries are targeted?

A: The use in food additives, pharmaceutical and healthcare, marine antifouling coatings as well as wire and cable anti-termite and anti-rodent industries.

Q5: What are the expected tests before bulk use?

A: Dispersion, compatibility, sensory strength, handling conditions, processing stability, and final product suitability.


Shipping Information

The usual lead time is 3 days after order confirmation if the Nonivamide is in stock at our warehouse.

For orders that require customized processing, special packaging, or non-standard preparation, production time is 15-25 working days.

25 kg/drum is the standard packaging for the product, but we also have 1 kg trial packs for sample evaluations.

Furthermore, Yihe Biomedical is always ready to talk with customers about the opportunity of setting up safety stocks of major products for repeat or large-volume orders to ensure continuous procurement and lower the supply interruption ‍‌‍‍‌risk.


CompanyHangzhou Yihe Biomedical Technology Co., Ltd.
Business LayoutHangzhou trade office for international business, customer communication, and logistics coordination; Nanning factory for production and quality control
Factory LocationNanning, Guangxi, close to botanical raw material sources
Factory OperationNanning factory officially started production in 2019
Factory AreaAbout 3,300 m²
Extraction Capacity7 extraction tanks, 6 tons each
Annual Raw Material CapacityOver 2,000 tons of botanical raw materials per year
Product FormsSingle compounds, standardized extracts, ratio extracts, compound granules, and customized grades
Quality DocumentsCOA, TDS, MSDS/SDS, specification sheet; Halal, Kosher, and organic documents available for selected products
Testing CapabilityHPLC, GC/MS, ICP-MS, GC-ECD / GC-MS, headspace gas chromatography, moisture, ash, and particle size testing
Sample SupportSamples can be supplied with sample COA and basic product information
MOQ ReferenceRegular extracts: 25 kg/drum; 1 kg trial pack available; customized products can be discussed from around 5 kg depending on process
Lead Time ReferenceStock products: around 3 working days; customized production: around 15–25 working days
TraceabilityEach batch has a unique batch number linked to raw materials, production records, test reports, and logistics records
Quality ResponseQuality complaints are handled within 48 hours with internal investigation and corrective action when needed


Nonivamide


  • Q1: Are you a factory or a trading company?

    We are a professional manufacturer integrating R&D, production, and sales. We control quality directly from the source. You are welcome to visit our factory.
  • Q2: What international certifications do you have?

    Our factory is ISO 9001 certified. Our core products comply with USP/EP standards. For most botanical extracts, we can also provide HALAL and KOSHER certifications.
  • Q3: What is the difference between ratio extracts and standardized extracts?

    Ratio extracts (such as 10:1) mean that 10 kg of raw material is used to produce 1 kg of extract, but the content of active compounds may vary. Standardized extracts, on the other hand, guarantee a specific percentage of active ingredients (such as 5% flavonoids), ensuring consistent efficacy from batch to batch. For pharmaceutical applications, we recommend standardized extracts.
  • Q4: Can you provide a Certificate of Analysis before shipment?

    Of course. Every batch is tested by our in-house quality control laboratory. We provide a detailed Certificate of Analysis (COA), including heavy metals, microbial limits, and active ingredient content. Third-party test reports (such as SGS or Eurofins) can also be provided upon request.
  • Q5: What is your minimum order quantity (MOQ)?

    For high-purity pharmaceutical raw materials, the MOQ is usually [e.g. 25 kg/drum]. For popular botanical extracts, we keep stock available, so sample orders or small trial orders (1–5 kg) are acceptable.
  • Q6: Can these ingredients be legally imported into the USA / EU / Japan?

    Our products comply with most international regulations. Please let us know your target market, and we will provide a regulatory assessment accordingly.
  • Q7: How do you ensure product stability during long-distance sea transportation?

    We use food-grade fiber drums with double-layer sealed inner bags. We can also provide stability data to support your shelf-life claims.

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